Malyasree Giri
Aarhus
Overview
12
12
years of professional experience
14
14
years of post-secondary education
Work History
Summer Research
Indian Association for the Cultivation of Science
- Synthesis of L-Alanine Conjugate of 2-naphthoxyacetic acid and its characterization
Postdoctoral Research
Aarhus University
1 2022 - Current
- BOUNDLESS Signalling in membrane-less organelles: A new phase in cellular biology
PhD and Research Associate
Indian Institute of Science
01.2014 - 01.2022
- Structural and DNA binding properties of ARID domains present in hSWI/SNF chromatin remodeling complex subunits
Master's Dissertation
Indian Institute of Technology Madras
01.2013 - 01.2014
- Synthesis And Spectroscopic Studies of Pyrene-Thiophene Conjugates
Education
Doctor of Philosophy (PhD) - Biophysics
Indian Institute Of Science (IISc)
01.2014 - 05.2020
Master of Science (M.Sc) - Chemistry
Indian Institute of Technology Madras
01.2012 - 05.2014
Bachelor of Science (B.Sc) - Chemistry
Lady Brabourne College, University of Calcutta
01.2009 - 05.2012
Higher Secondary (12th) - undefined
West Bengal Board of Secondary Education
01.2007 - 05.2009
Skills
NMR spectroscopy
Isothermal Titration Calorimetry (ITC)
Surface Plasmon Resonance (SPR)
Brightfield Microscopy
CD, DSC, SEC, SECMALS instruments, TSA, Labbot and Nanotemper prometheus panta
NMR softwares: Sparky, Poky, CCPN and Topspin
Data fitting and plotting softwares: Origin, Matlab, GraphPad Prism
Protein modeling and docking
Protein crystallization, DNA cloning, mutagenesis, and protein purification
Publications
- Structure and DNA binding analysis of AT-rich interaction domain present in human BAF-B specific subunit BAF250b, Protein Science, April 9, 2022, 10.1002/pro.4294
- Signatures of specific DNA binding by the AT-rich interaction domain of BAF250a, Biochemistry, Jan 14, 59(1):100-113, 10.1021/acs.biochem.9b00852
- SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity, Nucleic Acids Research, Aug 2, 10.1093/nar/gkz648
- Molecular Determinants of Complex Formation between DNA and the AT-rich Interaction Domain of BAF250a, FEBS Letters, Jul 19, 593(19) 2716-2729, 10.1002/1873-3468
- Sequential backbone resonance assignment of AT-rich interaction domain of human BAF200, Biomolecular NMR Assignments, Dec 10, 10.1007/s12104-018-9862-z
- Domain architecture of BAF250a reveals the ARID and ARM-repeat domains with implication in function and assembly of the BAF remodeling complex, Plos One, Oct. 11, 13(10):e0205267, 10.1371/journal.pone.0205267
Timeline
PhD and Research Associate
Indian Institute of Science
01.2014 - 01.2022
Doctor of Philosophy (PhD) - Biophysics
Indian Institute Of Science (IISc)
01.2014 - 05.2020
Master's Dissertation
Indian Institute of Technology Madras
01.2013 - 01.2014
Master of Science (M.Sc) - Chemistry
Indian Institute of Technology Madras
01.2012 - 05.2014
Bachelor of Science (B.Sc) - Chemistry
Lady Brabourne College, University of Calcutta
01.2009 - 05.2012
Higher Secondary (12th) - undefined
West Bengal Board of Secondary Education
01.2007 - 05.2009
Summer Research
Indian Association for the Cultivation of Science
Postdoctoral Research
Aarhus University
1 2022 - Current